Towards Drugs of the Future : Key Issues in Lead Finding and Lead Optimization.

By: Kruse, C.GContributor(s): Timmerman, H | Solvay Pharmaceutical Conference on Medicinal Chemistry | IOS PressMaterial type: TextTextSeries: Solvay Pharmaceutical Conferences, v. 9Publisher: Amsterdam : IOS Press, 2007Copyright date: ©2008Description: 1 online resource (140 pages)Content type: text Media type: computer Carrier type: online resourceISBN: 9781607503910Subject(s): Drug development -- Congresses | Pharmaceutical chemistry -- Congresses | Pharmaceutical industry -- CongressesGenre/Form: Electronic books.Additional physical formats: Print version:: Towards Drugs of the Future : Key Issues in Lead Finding and Lead OptimizationDDC classification: 615.1072 LOC classification: RS401 -- .S65 2007ebOnline resources: Click to View
Contents:
Title page -- Preface -- List of Contributors -- Contents -- Conference Preface and Keynote Lecture -- Conference Preface -- Keynote Lecture - Targets for Therapy. Are We Doing Anything Well? -- A Thermodynamic Platform for Drug Discovery and Optimization -- Structure-Based Design: Past, Present, and Future -- Sense and Nonsense in Drug Discovery: A Chemical Perspective -- Synthesis at the Interface of Chemistry and Biology: How and Why? -- Drug Design with ADME in Mind: Recent Paradigm Shifts in Drug Discovery -- Hypothesis Generation for Scientific Discovery. Examples from the Use of KEM®, a Rule-Based Method for Multi-Objective Analysis and Optimization -- Does Size Matter? Facts and Thoughts on Recombinant Drugs -- Can Nanotechnology Improve the Oral Delivery of Therapeutic Proteins? -- The Omeprazole Story: How Endurance in Research May Pay Off -- Conceptual Design of Cannabinoid CB1 Receptor Antagonists -- Author Index.
Summary: The number of novel medications in the global industry pipeline is insufficient to suffice demand of the markets, the financial performance of several companies is declining, and sales and marketing costs are rising. This title addresses the development in synthetic and medicinal chemistry with the emphasis on global challenges.
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Title page -- Preface -- List of Contributors -- Contents -- Conference Preface and Keynote Lecture -- Conference Preface -- Keynote Lecture - Targets for Therapy. Are We Doing Anything Well? -- A Thermodynamic Platform for Drug Discovery and Optimization -- Structure-Based Design: Past, Present, and Future -- Sense and Nonsense in Drug Discovery: A Chemical Perspective -- Synthesis at the Interface of Chemistry and Biology: How and Why? -- Drug Design with ADME in Mind: Recent Paradigm Shifts in Drug Discovery -- Hypothesis Generation for Scientific Discovery. Examples from the Use of KEM®, a Rule-Based Method for Multi-Objective Analysis and Optimization -- Does Size Matter? Facts and Thoughts on Recombinant Drugs -- Can Nanotechnology Improve the Oral Delivery of Therapeutic Proteins? -- The Omeprazole Story: How Endurance in Research May Pay Off -- Conceptual Design of Cannabinoid CB1 Receptor Antagonists -- Author Index.

The number of novel medications in the global industry pipeline is insufficient to suffice demand of the markets, the financial performance of several companies is declining, and sales and marketing costs are rising. This title addresses the development in synthetic and medicinal chemistry with the emphasis on global challenges.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2018. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.

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